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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THOC5
All Species:
17.58
Human Site:
T524
Identified Species:
32.22
UniProt:
Q13769
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13769
NP_001002877.1
683
78508
T524
S
R
L
V
K
W
V
T
V
A
H
E
D
Y
M
Chimpanzee
Pan troglodytes
XP_515059
683
78517
T524
S
R
L
V
K
W
V
T
I
A
H
E
D
Y
M
Rhesus Macaque
Macaca mulatta
XP_001106294
689
79038
T530
S
R
L
V
K
W
V
T
V
A
H
E
D
Y
M
Dog
Lupus familis
XP_534728
683
78595
T524
S
R
L
V
K
W
V
T
I
A
H
E
D
Y
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKT7
683
78667
I524
S
R
L
V
K
W
V
I
I
T
H
E
D
Y
M
Rat
Rattus norvegicus
Q68FX7
682
78642
I523
S
R
L
V
K
W
M
I
M
A
H
E
D
Y
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517072
363
40527
L213
P
Y
E
D
Y
L
E
L
P
Y
T
K
D
I
V
Chicken
Gallus gallus
Q5ZJK1
698
80563
A539
S
R
L
V
K
W
T
A
I
P
F
E
D
Y
T
Frog
Xenopus laevis
Q7ZXA8
678
77744
V519
S
R
L
T
K
W
N
V
I
A
Y
E
D
Y
L
Zebra Danio
Brachydanio rerio
Q6NY52
684
77815
M524
S
G
L
T
R
W
T
M
M
S
H
Q
E
F
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1F4
616
70871
E466
W
T
A
I
T
H
E
E
L
H
S
Q
I
S
D
Honey Bee
Apis mellifera
XP_396039
657
75378
T507
C
G
N
L
P
V
F
T
T
N
N
N
D
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798236
699
79519
T532
S
S
L
K
S
W
T
T
I
T
A
E
D
F
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
95.5
98
N.A.
96.1
96.1
N.A.
45.2
83.2
76.5
68.4
N.A.
25.7
37
N.A.
46.2
Protein Similarity:
100
100
96.3
99.1
N.A.
97.9
98.3
N.A.
49.7
90.9
87.1
83
N.A.
45.3
56.2
N.A.
65.2
P-Site Identity:
100
93.3
100
93.3
N.A.
80
80
N.A.
6.6
60
60
26.6
N.A.
0
13.3
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
86.6
93.3
N.A.
20
66.6
80
66.6
N.A.
20
33.3
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
8
0
47
8
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
0
85
0
8
% D
% Glu:
0
0
8
0
0
0
16
8
0
0
0
70
8
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
8
0
0
16
0
% F
% Gly:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
8
54
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
16
47
0
0
0
8
8
0
% I
% Lys:
0
0
0
8
62
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
0
0
77
8
0
8
0
8
8
0
0
0
0
8
16
% L
% Met:
0
0
0
0
0
0
8
8
16
0
0
0
0
0
47
% M
% Asn:
0
0
8
0
0
0
8
0
0
8
8
8
0
0
0
% N
% Pro:
8
0
0
0
8
0
0
0
8
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
8
% Q
% Arg:
0
62
0
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
77
8
0
0
8
0
0
0
0
8
8
0
0
8
0
% S
% Thr:
0
8
0
16
8
0
24
47
8
16
8
0
0
0
16
% T
% Val:
0
0
0
54
0
8
39
8
16
0
0
0
0
0
8
% V
% Trp:
8
0
0
0
0
77
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
0
0
0
0
8
8
0
0
62
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _